WITHOUT STRESS With cannabinoids
When overwhelmed with excessive anxiety associated with the invasion of coronavirus, we take care ofsystem
the immuneand alleviate stress and anxiety, which weaken the body’s ability to fight pathogens.
Until we finally recognize the nature of the Wuhan coronavirus and find measures that can destroy it, we must act on it indirectly. As more and more experts rightly point out, the key is to use common sense and ensure the best functioning of the immune system. When it is strong, your body will deal with any possible infection more easily. As you know, the stress and anxiety that accompany an epidemic affect immunity on the contrary, weakening our natural defense capacity. In this situation, cannabinoids may be a good solution – just one dose of CBD stimulates serotonin receptors, which increases the production of neurotransmitters and helps fight anxiety. What’s more, cannabidiol affects the body through the endocannabinoid system (EKAN) located in almost all of our body, which regulates not only well-being, sleep cycle and appetite, but also the functioning of the immune system burdened by excessive mental tension. This means that CBD is able to alleviate the negative effects of stress and thus improve the functioning of the entire body.
EKAN and the brain
The endocannabinoid system is involved in the regulation of the endocrine system because it inhibits and stimulates the hypothalamic-pituitary-gland axis in response to short- and long-term stress1.has
Research shown that the CB1 receptor knockout mice learn to fear a conditional response, but – contrary
to normal animals – it can not extinguish. This means that endocannabinoids play an important role in suppressing unpleasant feelings and pain caused by recalling previous experiences. Consequently, low receptor numbers or impaired endocannabinoid release can cause post-traumatic stress disorder, phobias and various forms of chronic pain2.
The role of neurotransmitters
Researchers at the University of Sao Paulo and King’s College in London have looked atknown
CBD’s long-relationship to stress, anxiety and anxiety. It turned out that in sufficiently high doses, cannabidiol has a calming effect not only by affecting the endocannabinoid system, but also by affecting serotoninreceptors3.
Chemically speaking, this neurotransmitter is a tryptamine derivative, often abbreviated as 5-HT. It binds to receptors of different types, and cannabidiol modifies
one of them (5-HT 1A), the dysfunction of which can cause depression and anxiety. CBD stimulates it, which results in increasing the production of serotonin and dopamine which help to combat symptoms of anxiety. Research has shown that stress is reduced after a single dose of cannabidiol.
Of course, it should not be forgotten that cannabinoids also directly affect the functioning
of the immune system – this is where CB2 receptors are found. Generally speaking, CBD stimulates natural immunity and helps maintain homeostasis, i.e. harmonious conditions inside the body, giving it a chance
to defend itself against pathogens4. Overall, cannabinoids provide a double benefit. Firstly, through CB2 receptors, they directly affect the better functioning of the immune system, and secondly – they strengthen it indirectly, reducing stress and anxiety, which are among the most important factors that weaken immunity.